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A 70 year old previously well female presents with a palpable breast mass. On clinical exam, she has a palpable, fixed and firm 4 by 4 lesion in the right upper outer quadrant, as well as peau d'orange. She undergoes mammography and core biopsy and is subsequently diagnosed with invasive ductal carcinoma. She wants to undergo mastectomy. What is the physiologic cause of peau d'orange?

Contributor: Trisha Maloney
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Kalil Janguiê commented on the question Which of the following is not a typical feature of a myocardial infarction in women?:
I have to agree with lizzibob, a myocardial infarction isn't relieved with rest/nitroglycerin.
Max Mitropoulos commented on the question Which of the following leads are most commonly examined for evidence of an anterior wall infarcti...:
Aspects of the heart in ECG: Inferior - II, III, aVF Anterior - V3 and V4 Septal - V1 and V2 Lateral - I, aVL, V6, V5 Beginner's trick: when...
Max Mitropoulos commented on the question Which of the following leads are most commonly examined for evidence of an anterior wall infarcti...:
Aspects of the heart in ECG: Inferior - II, III, aVF Anterior - V3 and V4 Septal - V1 and V2 Lateral - I, aVL, V6, V5
Aaron Harris commented on the question Gilbert's syndrome::
It also causes a rise in unconj. bilirubin, therefore abnormal LFTs?
Max Mitropoulos created a question: Which of the following statements regarding action of catecholamines on blood vessels and the he...
Max Mitropoulos created a question: Chest pain that is released by sitting up and leaning forward is classically caused by:
Max Mitropoulos created a question: All of the following causes of chest pain may be relieved by nitrolingual spray expect:
1S1K commented on the question Which of the following regarding Plan B emergency contraception is FALSE?:
And it doesn't disrupt implantation if it's already occurred
1S1K commented on the question In women with preexisting diabetes mellitus, risk of miscarriage and fetal anomaly substantially ...:
Then why do we say that post-conception poor glycemic control is a major contributor to macrosomia? I guess if we are saying macrosomia is not &qu...
1S1K commented on the question Which of the following is decreased during pregnancy?:
Pretty sure it's dilutional

 
 
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